Centennial · Denver Metro · Colorado

Hormone Therapy & Medical Weight Loss in Centennial, Colorado

Defiance Health is a cash-pay medical clinic in Centennial, Colorado — just off I-25 and Dry Creek, near the Denver Tech Center. We specialize in hormone optimization (BHRT and TRT) and medical weight loss with compounded GLP-1 medications. Real intake, real labs, and a real plan from a clinician who actually knows your numbers.

Schedule a Comprehensive Intake — $495 Call (719) 480-2400

Centennial Clinic

7354 S Alton Way, Suite 102 Centennial, CO 80112
Mon–Fri · 9 AM – 5 PM Telehealth available CO, AZ, CA, WA
Off I-25 & Dry Creek Near the Denver Tech Center
Get directions →
What We Specialize In

Two services. Done well. In Centennial.

Our Centennial patients come to us primarily for hormone optimization and medical weight loss. Both run on comprehensive labs, real provider time, and personalized protocols — not telehealth shortcuts. Our aesthetic technology is among the best in Denver Metro, but it's the medical work that defines us.

Specialty · GLP-1 Weight Loss

Medical Weight Loss in Centennial

Compounded semaglutide and tirzepatide — the same active ingredients as Wegovy, Ozempic, Mounjaro, and Zepbound — combined with full lab work, body composition tracking, and ongoing provider support.

  • Compounded semaglutide & tirzepatide injections
  • InBody body composition analysis on-site
  • Full metabolic panel and ongoing lab monitoring
  • Programs from $200/mo after intake
Explore the program Specialty · BHRT & TRT

Hormone Therapy in Centennial

Bioidentical hormone optimization for testosterone, estrogen, progesterone, and thyroid. Comprehensive labs, dosing built from your data, and a provider relationship that actually adjusts your protocol over time.

  • BHRT for women — perimenopause & menopause
  • TRT for men — testosterone optimization
  • Thyroid & comprehensive hormone panels
  • Programs from $135/mo (women), $200/mo (men)
Explore hormone therapy
How Defiance Works

The intake is the medicine.

Most clinics treat the visit like a transaction — a five-question form, a prescription, a follow-up if you can find one. We treat it like the foundation. Here's what your first $495 actually buys you.

01

Comprehensive Lab Panel

Full hormone, metabolic, thyroid, inflammation, and nutrient panel — drawn at your visit and reviewed by a provider before any treatment plan is built. No shortcuts, no template panels.

02

75-Minute Provider Visit

You sit with a clinician who reviews your labs, history, symptoms, and goals. The plan is built from your data — not a template. If treatment doesn't fit, we say so.

03

Real Plan + Real Follow-Up

Your protocol is built on what your numbers actually say. We re-check labs, adjust dosing, and refine the plan as you respond. Telehealth check-ins and provider messaging included.

Also Available in Centennial

Best-in-Class Aesthetics & Adjacent Care

Our Centennial clinic carries some of the most advanced aesthetic technology in Denver Metro — frequently used by our hormone and weight loss patients to support the changes they're seeing.

Medical Aesthetics

EMFACE facial sculpting, EMSCULPT NEO body contouring, EXION RF microneedling, BBL Hero, MOXI laser, and neurotoxin injectables.

Explore aesthetics →

Peptide Therapy

BPC-157, CJC-1295, Ipamorelin, and other clinically prescribed peptides — supervised, lab-monitored, and through licensed pharmacies.

Explore peptides →

IV Therapy & Vitamin Shots

Custom IV drips, B12, glutathione, NAD+, immune and recovery formulations. Drop-in or scheduled appointments at our Centennial clinic.

Explore IV therapy →
Visit Defiance Health Centennial

Convenient access from across Denver Metro

Our Centennial clinic is located off I-25 and Dry Creek Road, just minutes from the Denver Tech Center. We serve patients from across the south Denver Metro and beyond — Centennial, Greenwood Village, Englewood, Highlands Ranch, Lone Tree, Parker, and Aurora.

  • Free parking — surface lot directly in front of the building
  • I-25 access — Dry Creek exit, 2 minutes from the highway
  • Telehealth available — for ongoing visits across Colorado, Arizona, California, and Washington
  • Minutes from DTC — accessible to professionals working in the Denver Tech Center

Centennial Clinic Details

Address 7354 S Alton Way, Suite 102
Centennial, CO 80112
Phone (719) 480-2400
Hours Monday – Friday
9:00 AM – 5:00 PM
Directions Get directions on Google Maps →
Serving Denver Metro

Patients travel to our Centennial clinic from across the south Denver Metro.

Whether you're in Centennial, Greenwood Village, Highlands Ranch, or further south, our location off I-25 makes us accessible from anywhere in the south metro corridor.

Centennial Greenwood Village Englewood Highlands Ranch Lone Tree Parker Aurora Littleton Cherry Hills Village DTC South Denver
Frequently Asked Questions

Centennial Clinic FAQ

Our Centennial clinic is at 7354 S Alton Way, Suite 102, Centennial, CO 80112 — just off I-25 and Dry Creek Road, minutes from the Denver Tech Center. Free parking is available directly in front of the building.
The intake is a flat fee that covers your full lab panel (drawn on-site), body composition analysis with InBody, and a 75-minute visit with a Defiance Health provider who reviews your labs, history, and goals before building a treatment plan. No upsells. Lab results return in 3-5 days, and your follow-up is included as part of the program you elect to start.
Defiance Health is a cash-pay clinic. We provide every patient with a detailed superbill that you can submit to your private insurance for potential out-of-network reimbursement. We accept HSA and FSA cards, and we offer financing through CareCredit and Cherry to make care more accessible.
No referral is required. Patients book directly with Defiance Health for hormone therapy, medical weight loss, peptide therapy, aesthetics, IV therapy, or direct lab testing.
Telehealth-only weight loss programs typically provide a brief online intake followed by a prescription — without comprehensive labs, body composition analysis, or a real provider relationship. At our Centennial clinic, every patient gets a full lab panel drawn on-site, an InBody body composition scan, and a 75-minute provider visit before any prescription is written. Treatment plans are personalized to your data and adjusted as you respond.
Yes. After your in-person intake at the Centennial clinic, ongoing follow-ups can be handled via telehealth for patients in Colorado, Arizona, California, and Washington. Lab work can be drawn at any Quest or Labcorp location convenient to you. We do recommend in-person visits for body composition tracking when possible.
We treat adult patients 18 and older. Our hormone therapy and medical weight loss patients typically range from late 20s through 60s and beyond. Programs are individualized based on your specific health profile, labs, and goals.
On April 30, 2026, the FDA proposed excluding semaglutide and tirzepatide from the 503B bulks list. The proposal targets large-scale outsourcing facilities and does not directly change the rules for the patient-specific 503A pharmacies we partner with. Active prescriptions are not interrupted. Read our full clinical breakdown.
Ready to Start?

Schedule your Centennial intake today.

Book a comprehensive intake at our Centennial clinic — full labs, body composition, and a 75-minute provider visit for a flat $495.

Book Your Intake Call (719) 480-2400