Tired All the Time? Let's Find Out Why.
Being told "your labs look normal" when you can barely get through the day isn't an answer. At Defiance Health, we run the comprehensive workup that most clinics skip — and we actually treat what we find.
"Everything came back normal."
"It's probably just stress."
"Have you tried getting more sleep?"
If you've heard these answers and your body is still telling you something's wrong, you're in the right place. Fatigue is a symptom — not a diagnosis. Finding the root cause takes comprehensive testing and a provider who's actually willing to look.
What Chronic Fatigue Actually Looks Like
This isn't "I should probably go to bed earlier." This is your life being changed by exhaustion that doesn't respond to rest. If any of these sound familiar, it's worth investigating.
Morning exhaustion
Waking up feeling like you didn't sleep, even after 8+ hours
Afternoon crashes
Hitting a wall between 2-4 PM that coffee can't fix
Brain fog
Trouble focusing, word-finding issues, feeling "slow"
Unexplained weight changes
Gaining weight despite no change in diet, or losing it
Mood changes
Irritability, low mood, or anxiety without clear cause
Exercise intolerance
Workouts leave you wrecked for days instead of energized
Low libido
Drop in sex drive that wasn't there 6-12 months ago
Cold intolerance
Always cold, cold hands and feet, feeling "run down"
Hair loss or skin changes
Thinning hair, dry skin, brittle nails — signs of deficiency
Nine Things That Could Actually Be Wrong
Chronic fatigue has real, identifiable causes. Most are missed because standard primary care visits don't include the right labs. Here's what we evaluate — and where the fix often lives.
Thyroid Dysfunction
An underactive thyroid is one of the most common — and most misdiagnosed — causes of fatigue. TSH alone isn't enough; you need the full panel to catch it.
Hormone Imbalance
Low testosterone in men, estrogen/progesterone dynamics in women, and perimenopause in women 35+ are enormously underdiagnosed causes of fatigue.
Iron Deficiency
You can be iron-deficient with a "normal" CBC. Ferritin — your body's iron storage marker — is what actually matters, and it's rarely tested by standard primary care.
Vitamin D Deficiency
Especially common in Colorado winters. Low D drives fatigue, mood changes, immune dysfunction, and accelerated aging. Easy to test, easy to fix.
B12 & Methylation
B12 deficiency causes fatigue, brain fog, nerve tingling, and mood changes. MTHFR gene variants can make oral B12 poorly absorbed — that's why injectable methyl-B12 often works when pills don't.
Adrenal & Cortisol Pattern
Chronically elevated or depleted cortisol from long-term stress disrupts energy, sleep, weight, and hormones. A single morning cortisol isn't enough — the pattern across the day matters.
Insulin & Blood Sugar
Early insulin resistance causes fatigue long before diabetes shows up on bloodwork. Fasting insulin is the key marker — and it's almost never tested in standard physicals.
Sleep Disorders
Sleep apnea is dramatically underdiagnosed in women. Poor sleep architecture from hormone shifts, stress, or sleep-disordered breathing can cause chronic fatigue even with 8 hours in bed.
Chronic Inflammation
Low-grade chronic inflammation from autoimmune conditions, gut issues, or lifestyle factors is a major driver of fatigue. CRP and other inflammatory markers tell the story.
Most fatigue patients have more than one cause. We don't stop at finding one — we build a complete picture so we can treat the actual drivers, not just one piece.
From "Normal" to Actual Answers
Deep Intake
A real conversation about symptoms, history, timeline, and how fatigue is affecting your life.
Comprehensive Labs
A full panel based on your history — not the minimal default. Results typically in 5-7 days.
Results Review
We sit down and walk through what we found, what it means, and what we'd recommend doing about it.
Treatment & Follow-Up
Targeted treatment — hormones, thyroid, nutrients, peptides, lifestyle — with lab rechecks to confirm it's working.
What You Won't Hear from Us
- "Everything looks normal."
- "Have you tried meditation?"
- "It's probably just stress."
- "You just need to exercise more."
- "Maybe you're depressed."
- "That's just part of getting older."
- "Your TSH is fine, so your thyroid is fine."
- "We don't usually test for that."
Fatigue Questions, Answered
Book a Root-Cause Evaluation
In-office at Centennial or Alamosa, or via telehealth in Colorado, Arizona, California, and Washington. A real conversation about what's going on — and a plan to find out why.
Centennial / Denver
7354 S Alton Way, Suite 102
Centennial, CO 80112
Mon–Fri · 9 AM – 5 PM
Alamosa · San Luis Valley
315 Edison Ave, Suite B
Alamosa, CO 81101
Mon–Fri · 9 AM – 5 PM
Telehealth
Colorado · Arizona · California · Washington
Full evaluation via video visit
Labs at nearby Quest or LabCorp